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Connecting Roche cobas pure integrated solutions to your LIS or EHR
Quick answer
Yes. Roche publishes a host interface for cobas pure based on HL7 version 2.5 over an Ethernet TCP/IP connection, with the control unit acting as client or server. It sends a test selection inquiry for each sample, so Catenix replies with the tests ordered in your EHR and takes back patient, control and calibration results. IP address, port and role are set on the control unit during setup.
cobas pure integrated solutions is Roche's compact serum work area system: a sample supply unit with up to two analytical units on a footprint of about two square metres. The cobas c 303 runs clinical chemistry with built-in ISE at up to 450 photometric tests an hour (750 an hour in mixed mode), and the cobas e 402 runs immunoassays at up to 120 tests an hour.
Between them the units cover more than 110 chemistry applications and more than 100 immunoassays from one sample tube. Racks load continuously, 50 samples at a time, past an integrated barcode reader, and STAT samples have a dedicated port. Roche positions the system for small and satellite laboratories short of space, and quotes about five minutes of operator maintenance a day.
| What | How Catenix handles it |
|---|---|
| Configuration | Sample supply unit plus cobas c 303 and/or cobas e 402 |
| Chemistry speed | Up to 450 photometric tests/hour; 750 mixed with ISE |
| Immunoassay speed | Up to 120 tests/hour |
| Host protocol | HL7 version 2.5 |
| Network | Ethernet TCP/IP, client or server, default port 54000 |
| Order modes | Real-time test selection inquiry, or batch |
| Sent to host | Patient, control and calibration results; instrument and inventory status |
Test selection inquiry, rack by rack
When cobas pure detects a rack it asks the host what to run, one sample at a time in position order, and waits for the reply up to a timeout you set. Catenix answers each inquiry with the EHR's tests for that barcode. Orders can also be registered ahead of time by batch communication.
Several inquiry options are worth settling before go-live: whether to ask again for automatic or manual reruns, whether to always ask on a first run, and whether to ask the host when a barcode cannot be read. The host can also add a reflex test to a sample as an automatic rerun order.
Client or server on the lab network
The control unit speaks HL7 over Ethernet, so no serial adapter is involved. You choose whether cobas pure opens the connection or waits for the host to connect, and set the port: 54000 unless changed. The Catenix gateway on your LAN takes the other side, re-establishes the session if the network drops, and stores results on site while the internet is down.
Chemistry, ISE and immunoassay test codes are each mapped to an EHR code during setup. Every HL7 message is kept with its result, and a result matching no order waits for review.
Controls, calibration and masked tests
Result reports from cobas pure cover control and calibration measurements as well as patient samples. Catenix files the controls as QC, grades them with Westgard rules against your targets and charts them on Levey-Jennings plots; a failed control holds patient results for that test. cobas pure also reports instrument status and test availability to the host, including tests masked by QC or calibration.
Roche and cobas pure are trademarks of their owners. Catenix is an independent connectivity provider, not affiliated with or endorsed by Roche.
Questions people ask
Does cobas pure use HL7 or ASTM?
Roche's host interface manual for cobas pure describes an HL7 channel, compliant with HL7 version 2.5, over Ethernet.
Does cobas pure support host query?
Yes. It sends a test selection inquiry for each sample on a rack and Catenix replies with the EHR's orders. Batch order registration is also available.
Which TCP port does cobas pure use?
54000 by default, with 54001 to 54009 or a custom port selectable on the control unit.
Related: Roche cobas c 311 connection · Roche cobas e 411 connection · HL7, POCT1-A2 and ASTM explained · Device library
Product and company names are trademarks of their owners and are used for identification only. Catenix moves, stores and displays results with traceability; it does not interpret results or give clinical advice. Reviewed November 2026.
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